Drug That May Produce More Insulin
By Kathleen Blanchard RN for eMaxHealth.com
Researchers at Toronto Western Research Institute have made an important discovery that could help people with diabetes produce more insulin. In their study, they discovered VAMP8, which is a SNARE protein – soluble N-ethylmaleimide-sensitive-factor attachment protein receptor – plays an important role in insulin release from the pancreas. Understanding the role of the protein means newer drugs can be developed to better treat both type 1 and type 2 diabetes.
VAMP8 protein induces insulin release
Dr. Herbert Gaisano, a researcher at the Toronto Western Research Institute, Professor of Medicine and co-director of the Centre for Research in Diet, Digestive Tract and Disease has been able to show VAMP8 is crucial for insulin secretion because it prompts “newcomer insulin secretory granules” to fuse to plasma membranes.